Montreal Canadiens at Toronto Maple Leafs, 7 p.m. ET (SN, TVAS, ESPN+, NHL LIVE)
Auston Matthews, who led the NHL with 41 goals last season, will miss Toronto's season opener while he continues to recover from wrist surgery. The Canadiens defeated the Maple Leafs in seven games in the Stanley Cup First Round last season on their way to an appearance in the Stanley Cup Final, which they lost to the Tampa Bay Lightning in five games.
New York Rangers at Washington Capitals, 7:30 p.m. ET (TNT)
Capitals coach Peter Laviolette is one win shy of passing John Tortorella (673) as the winningest United States-born coach in NHL history. Based on opening night rosters, the Rangers are the third-youngest team in the NHL with an average age of 26.05, behind the Columbus Blue Jackets (25.71) and New Jersey Devils (25.74).
Winnipeg Jets at Anaheim Ducks, 10 p.m. ET (SN360, SN1, BSSC, BSSD, ESPN+, NHL LIVE)
The Ducks and Jets play the first of three games in 14 days to open the season. Forward Mason McTavish, the No. 3 pick in the 2021 NHL Draft, could make his NHL debut for Anaheim. Winnipeg will be without center Mark Scheifele (NHL suspension), but forward Cole Perfetti, the No. 10 pick in the 2020 NHL Draft, is expected to make his NHL debut.
Chicago Blackhawks at Colorado Avalanche, 10 p.m. ET (TNT)
The Avalanche are 23-11-7 (.646) points percentage) in season openers, the second-best record in the NHL behind the Tampa Bay Lightning (19-8-2; .690). Goalie Marc-Andre Fleury, who will make his Blackhawks debut, is eight wins from 500 in the NHL.
Vancouver Canucks at Edmonton Oilers, 10 p.m. ET (SN, ESPN+, NHL LIVE)
Oilers forward Leon Draisaitl looks for his 200th NHL goal in the season opener against the Canucks. Draisaitl has scored 199 goals in 478 games over seven seasons. The Canucks could be without forward Brock Boeser, who has an undisclosed injury.