Ovechkin, who was suspended for missing the 2020 Honda NHL All-Star Game in St. Louis, has eight goals in his past three games, including hat tricks in each of his past two games. He needs one goal to pass Steve Yzerman (692) for sole possession of ninth place on the NHL all-time list and two goals to tie Mark Messier (694) for eighth place.
Washington, which defeated the Montreal Canadiens 4-2 on Monday without Ovechkin, has won four straight games and is 7-2-0 in its past nine games.
The Predators have won seven straight games against the Capitals since a 4-1 loss March 18, 2016.
Nashville is 4-7-1 in its past 12 games after going 6-2-2 in its previous 10.