Canucks defenseman Eric Gudbranson said he hoped the fans enjoyed their first look at the NHL.
"It was really fun," Gudbanson said. "To begin with, this is a beautiful rink and they took to the game really well. I'm hoping they had fun and appreciated what we had to offer."
The Kings scored twice in the first period, once in the second and twice in the third to back goaltender Jonathan Quick, who made 31 saves. Forwards Adrian Kempe and Jeff Carter and defenseman Alec Martinez scored for Los Angeles, and defenseman Jake Muzzin had three assists.
Forwards Sven Baertschi and Markus Granlund scored for Vancouver.
Kempe earned the distinction of scoring the first NHL goal in China when his power-play slap shot from the top of the left circle beat Canucks goaltender Jacob Markstrom at 7:06 of the first period.
"I was happy I was the first guy to score, obviously," said Kempe, a 21-year-old who had six points (two goals, four assists) in 25 games for the Kings last season. "We got a good start, it was a nice shot, so I was glad."
Pearson made it 2-0 with an unassisted shorthanded goal at 15:18, scoring on a breakaway after intercepting a pass by Canucks forward Thomas Vanek.
"I didn't like our first period," Canucks coach Travis Green said. "I thought our play with the puck wasn't good enough. I thought [the Kings were] good with the puck in the first compared to us. I like how we played the last two periods."
Martinez made it 3-0 at 1:04 of the second period, but Baertschi made it 3-1 with his power-play goal at 2:15 of second period and Granlund made it 3-2 at 12:37 of the third period.
Pearson gave the Kings a 4-2 lead with 3:03 left when he scored on another breakaway, and Carter scored into an empty net with 51 seconds remaining.