OTTAWA -- Pittsburgh Penguins defenseman Justin Schultz and forwards Bryan Rust and Patric Hornqvist will miss Game 3 of the Eastern Conference Final against the Ottawa Senators at Canadian Tire Centre on Wednesday (8 p.m. ET; NBCSN, CBC, TVA Sports), each because of an upper-body injury.
The best-of-7 series is tied 1-1 after the Penguins won Game 2 1-0 in Pittsburgh on Monday.
Defenseman Trevor Daley will participate in warmups, and coach Mike Sullivan said he will be a game-time decision after missing four games with a lower-body injury. Defenseman Mark Streit, who has yet to play in the Stanley Cup Playoffs this season, also will be a game-time decision.
Sullivan said it is possible the Penguins will use seven defensemen and 11 forwards. If the Penguins go with six defensemen and 12 forwards, it appears forward Tom Kuhnhackl will re-enter the lineup after being a healthy scratch the past three games.
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Defenseman Kris Letang is out for the remainder of the season following neck surgery. Forwards Sidney Crosby (concussion) and Conor Sheary (concussion), goaltender Matt Murray (lower body) and Daley have missed time before returning.
"I just think it's a challenge that this league presents," Sullivan said. "Every team goes through it. We've had our fair share of it, maybe a little bit more than most, but what I love about this group of players is no one's looking for excuses. Everybody's looking for answers.
"The guys that get opportunities to go back into the lineup, they go in with the mindset that they want to make a difference, and I think that's just a credit to the character of the players that we have."
Schultz, Rust and Hornqvist are day to day, and Sullivan sounded optimistic they won't be out much longer.
"We're hopeful that they're making progress," Sullivan said.
Rust and Hornqvist skated together for about 25 minutes before the morning skate at the University of Ottawa but were in track suits and helmets. Schultz later went on the ice before the rest of the Penguins in full equipment and skated for about five minutes before speaking with members of the medical staff and leaving.
Rust, who has five goals in 14 playoff games, was injured on an open-ice hit by Senators defenseman Dion Phaneuf 4:58 into the first period on Monday. Schultz, who has eight points (two goals, six assists) in 14 playoff games, was injured on a hit by Senators forward Mike Hoffman 9:30 into the first period of Game 2.
Hornqvist was scratched for Game 2 after leaving warmups early. He has seven points (four goals, three assists) in 13 playoff games.
Video: Looking at Wednesday's matchup between Pens and Sens
Daley participated in the full morning skate and was paired with regular defense partner Olli Maatta. It was Daley's first time on the ice with the full team since he was injured in Game 5 of the Eastern Conference Second Round against the Washington Capitals. He had been skating on his own for three or four days, he said.
"I was hoping to try to be ready for [Game 3]," Daley said. "When I went down, I was frustrated. I missed a lot of time last year [with a broken ankle], so it was not where I wanted to be. But I'm excited with the progress I've made in the last week."
Streit, who hasn't played since the regular-season finale against the New York Rangers on April 9, was acquired from the Tampa Bay Lightning (who acquired him from the Philadelphia Flyers earlier in the day) on March 1 for a fourth-round pick in the 2018 NHL Draft. But the 39-year-old has been a healthy scratch throughout the playoffs.
"It's a big challenge," Streit said. "I haven't played in a while, but I'm just thrilled and excited if I get to play, and I'm looking forward to it."
Streit had 27 points (six goals, 21 assists) in 68 games during the regular season, including one goal and five assists in 19 games with the Penguins. In 31 NHL playoff games, Streit has 13 points (four goals, nine assists).
He was not on one of the top three defense pairs during line rushes at the morning skate but did work on the first power-play unit with Crosby and forwards Evgeni Malkin, Phil Kessel and Jake Guentzel. Sullivan said if Streit plays, he will use him on the power play.
The Penguins went 0-for-6 on the power play in the first two games of the series. Crosby spent some time talking with Streit at the end of the morning skate to review strategy.
"He hasn't actually played [in the playoffs], so I was just kind of giving him an idea of what we're looking for and kind of seeing what he sees out there too," Crosby said. "You try to prepare as much as you can. You don't know how many power plays you're going to get, so you want to make the most of the ones you get."