At 7:35 of the first period in the Canucks/Penguins game, Pittsburgh requested a Coach's Challenge to review whether Vancouver's Michael Chaput interfered with Pittsburgh goaltender Matt Murray prior to his goal.
After reviewing all available replays and consulting with NHL Hockey Operations staff, the Referee determined that Chaput interfered with Murray before the puck crossed the goal line. According to Rule 78.7, "The standard for overturning the call in the event of a 'GOAL' call on the ice is that the Referee, after reviewing any and all available replays and consulting with the Toronto Video Room, determines that the goal should have been disallowed due to 'Interference on the Goalkeeper,' as described in Rules 69.1, 69.3 and 69.4."

Therefore the original call is overturned - no goal Vancouver Canucks.
Since the Coach's Challenge resulted in the original call being overturned, the Pittsburgh Penguins retain their time-out.