Philadelphia Flyers at Boston Bruins, 7 p.m. ET (SN, TVAS, NESN, NBCSP, NHL.TV)
The Bruins and their struggling offense (three goals, two on the power play) look to avoid their third consecutive loss. The Flyers are without center Sean Couturier (rib), forward Morgan Frost (shoulder) and defenseman Philippe Myers (rib).
New Jersey Devils at New York Islanders, 7 p.m. ET (MSG+, MSG+ 2, NHL.TV)
Hughes' six points are tied with Kyle Palmieri, Jesper Bratt, Brian Gionta, John MacLean, Mel Bridgeman and Greg Adams for the Devils record through the first three games of a season.
Tampa Bay Lightning at Columbus Blue Jackets, 7 p.m. ET (NBCSN, FS-O)
The Lightning will try to become the first defending Stanley Cup champions to start the following season 3-0-0 since the Dallas Stars in 1999-00. The 1920-21 Ottawa Senators and 1985-86 Edmonton Oilers share the NHL record (5-0-0).
Winnipeg Jets at Ottawa Senators, 7 p.m. ET (TSN5, RDS, TSN3, NHL.TV)
The Jets take a struggling penalty kill, they've allowed four goals while shorthanded nine times (55.6 percent), into the second of three straight games against the Senators.
Montreal Canadiens at Vancouver Canucks, 9:30 p.m. ET (NBCSN, SNP, TSN2, RDS)
The Canadiens and Canucks play the second of a back to back at Rogers Arena. Vancouver started 0-for-15 on the power play before going 3-for-6 in a 6-5 shootout win Wednesday.
Colorado Avalanche at Los Angeles Kings, 10 p.m. ET (ESPN+, SN360, SNE, SNO, SNW, FS-W, ALT, NHL.TV)
Avalanche center Nathan MacKinnon has at least one shot on goal in 223 consecutive games, four behind Joe Sakic's Colorado/Quebec Nordiques record set from 1995-99.
Florida Panthers at Carolina Hurricanes -- Postponed