SAN JOSE -- Jake DeBrusk had a goal and an assist, and Anton Khudobin made 36 saves to help the Boston Bruins to a 3-1 win against the San Jose Sharks at SAP Center on Saturday.
Peter Cehlarik scored his first NHL goal, and Danton Heinen scored for the Bruins (8-7-4).
[WATCH: All Bruins vs. Sharks highlights]
Khudobin, who made his second straight start in place of No. 1 goaltender Tuukka Rask, defeated the Sharks for the second time this season. He is 4-1-0 in five career games against San Jose.
"It was good," Khudobin said. "We did a [heck] of a job too in front, blocked a lot of shots. We played a full 60 minutes too. I did make a couple saves."
All three Bruins goals were scored by rookies.
"I personally saw it all last year at Providence (in the American Hockey League), watched these guys that are playing with us now, including myself," DeBrusk said. "It's always nice to see. We want it so bad and we try to work as hard as we can to help this team in any way."
Video: BOS@SJS: Cehlarik pots rebound for his first NHL goal
Timo Meier scored, and Aaron Dell made 17 saves for the Sharks (10-8-0), who have scored two or fewer goals in five of their past six games.
"We've got to keep working," Sharks captain Joe Pavelski said. "We've got to dig a little bit harder around the net. We had some good chances tonight, but we were one play off."
San Jose outshot Boston 17-5 in the first period, but the Bruins built a 2-1 lead on goals by Cehlarik and DeBrusk.
"Busy, busy," Khudobin said of the first period. "But I like that. You don't have to think about anything else."
Heinen made it 3-1 at 14:09 of the third period with his fourth goal of the season and third against San Jose. He took a cross-crease pass from Kevan Miller on a rush and beat Dell from close range.
"He made a heck of a play," Heinen said of Miller. "He went end-to-end there. I just had my stick on the ice. It was a great play by him."
San Jose had a goal disallowed 1:02 into the game when it was determined after video review that Joonas Donskoi batted the puck into the net with his glove.
Video: BOS@SJS: Meier opens scoring on O'Regan's great pass
San Jose took a 1-0 lead at 4:50 of the first period on Meier's second goal of the season. Daniel O'Regan won a battle for the puck behind the net and sent a cross-crease pass to Meier, who beat Khudobin with a wrist shot.
Cehlarik tied it 1-1 at 6:17 of the first period. Dell stopped DeBrusk's initial shot off a rush, but Cehlarik scored on the rebound.
Dell was knocked to the ice before Cehlarik scored, and Sharks coach Peter DeBoer challenged for goaltender interference. The goal stood after it was determined Joakim Ryan tripped DeBrusk, sending him into Dell.
"I took a swipe at the puck, and I guess my stick hit [DeBrusk's] skates," Ryan said.
The Sharks had two goals negated on coach's challenges in a 2-0 loss to the Florida Panthers on Thursday. They had two reviews go against them Saturday.
DeBrusk scored on a breakaway at 10:46, three seconds after a Sharks power play expired, to give the Bruins a 2-1 lead. Charlie McAvoy cleared the puck deep down the right side, and DeBrusk tracked it down and beat Dell to the far side.
"It was a weird play from the start," DeBrusk said. "I remember Charlie kind of shot it out. I think it hit a stanchion or something or off the glass even, because I didn't even know where the puck was. I looked and it was kind of traveling to that dot area. I thought for sure [Dell] was going to come out, but it's a pretty fast game out there."
Video: BOS@SJS: Khudobin closes the pads to deny Hertl
Goal of the game
Heinen's goal at 14:09 of the third period.
Video: BOS@SJS: Heinen drives net to put home Miller's pass
Save of the game
Khudobin against Tomas Hertl at 11:40 of the third period.
Video: BOS@SJS: Khudobin denies Hertl's wrister down low
Highlight of the game
DeBrusk's goal at 10:46 of the first period.
Video: BOS@SJS: DeBrusk's impressive breakaway marker
They said it
"It's hard for it not to be a wakeup call in a sense. It's never good being healthy scratched. I take that personally." -- Bruins forward Jake DeBrusk on having a goal and two assists in two games after being a healthy scratch
"We got enough looks tonight to score. We're doing more good than bad. We're just not being rewarded." -- Sharks coach Peter DeBoer
Need to know
Bruins defenseman Torey Krug (upper body) missed his second straight game and remained day-to-day. ... O'Regan was called up from San Jose's AHL affiliate and played his first NHL game of the season. He replaced Barclay Goodrow (upper body), who was placed on injured reserve.
Bruins: At the New Jersey Devils on Wednesday (7 p.m. ET; MSG+2, NESN, NHL.TV)
Sharks: Host the Anaheim Ducks on Monday (10:30 p.m. ET; NBCSCA, FS-W, SN, NHL.TV)
Video: Khudobin makes 36 saves in Bruins' 3-1 win vs. Sharks