The goalie, who sustained a right-knee injury in a 7-5 loss at the Vancouver Canucks on Jan. 2, missed two games before dressing as the backup to Corey Crawford in a 5-2 loss to the Nashville Predators on Thursday.
Lehner is 12-7-4 with a 2.92 goals-against average and .922 save percentage this season for the Blackhawks, who have lost two straight after going 4-1-0 in their previous five games.
The Ducks, who have lost three consecutive road games and are 6-13-2 away from home this season, begin a five-game trip heading into the NHL All-Star break.
Goalie John Gibson will start for Anaheim, which has lost two straight overall and is 3-7-1 in its past 11.