Speaking to reporters immediately after the game, Head Coach Dave Tippett said it was too soon to offer detailed information on the extent of Smith's injury. He said the team would know more on Wednesday.
"We'll make sure we do our due diligence, find out what it is and we'll probably have more (information) tomorrow," Tippett said.
Smith fell to the ice in pain after getting twisted in the crease while lunging to make a save. He was helped off the ice and replaced by backup Louis Domingue at 7:18 of the third period.
Smith stopped 27 of 30 shots before suffering the injury. Domingue stopped 8 of 11 shots in relief.
• Rookie Dylan Strome made his NHL debut on Tuesday and assisted on Arizona's first goal, scored by Tobias Rieder at 12:18 of the first period. It was Strome's first NHL point.
Strome's parents were among the spectators to witness his debut at the Canadian Tire Centre. His billet parents also attended the game. Strome grew up in Mississauga, Ontario, which is about 300 miles from Ottawa.
Strome played 16:28 and won two of three face-offs.