After a scoreless opening 20 minutes, the Panthers struck first at 4:43 of the middle frame as Evgenii Dadonov tapped a loose puck home with a backhander at the side of Robin Lehner's net for a 1-0 lead.
Frank Vatrano scored the first of his three goals on the night 91 seconds later, beating Lehner glove-side from the top of the circle at the 6:14 mark of the second to make it a 2-0 game.
Vatrano would strike again at the 10:04 mark of the second, putting a shot five-hole off a rush for a 3-0 lead.
The birthday boy Dach got the Blackhawks on the board at the 13:33 mark, doing his best Kane impersonation on No. 88's night by going top shelf with a backhander over Sergei Bobrovsky's shoulder off the rush.