The forward, who has scored 26 goals, missed a 3-2 loss at the Edmonton Oilers on Saturday with a lower-body injury. He took part in Winnipeg's morning skate and is a game-time decision.
The Jets are tied with the Nashville Predators and Arizona Coyotes for the second wild card into the Stanley Cup Playoffs from the Western Conference.
Goalie Connor Hellebuyck will start for Winnipeg, which is 1-3-1 in its past five games after going 6-2-0 in its previous eight.
The Sabres, who defeated the Jets 2-1 in Buffalo on Feb. 23, have lost three straight.
Goalie Carter Hutton is expected to start for Buffalo. He has a .973 save percentage in his past five games against Winnipeg and is 5-5-1 with a 2.02 goals-against average and .935 save percentage in 12 games against the Jets/Atlanta Thrashers franchise.