During the second period, Harding was slow to get up several times but finished the period. Niklas Backstrom, who hadn't played since Oct. 8 as he was recovering from a knee injury, took over in goal for the Wild.
Harding stopped 20 of 21 shots faced through 40 minutes. He entered the evening as the NHL's leader in both goals-against average and save percentage.
Harding was the second goalie in the game to leave due to injury. Carolina's Cam Ward was injured in the first period and will miss 3-4 weeks with a lower-body injury.
Backstrom stopped all seven shots he faced. Justin Peters, who took Ward's place, stopped 19 of 21 shots he saw.
Minnesota won the game 3-1.