With two assists in Detroit's 5-3 win against the Ottawa Senators at Canadian Tire Centre on Saturday, Zetterberg reached 800 points in his NHL career.
The previous night, during a 3-1 loss to the Senators at Joe Louis Arena, Zetterberg scored his 299th goal.
He is the ninth Swedish player with 800 points in the NHL.
Zetterberg's next goal will make him the seventh Swede to score 300 and the fifth player in Red Wings history to have 300 goals and 800 points, joining Gordie Howe, Steve Yzerman, Alex Delvecchio and Sergei Fedorov.
The Red Wings host the Tampa Bay Lightning on Tuesday (7:30 p.m. ET; SUN, FS-D).