He replaces Brad Treliving, who became the Calgary Flames' general manager in April, and will work under Coyotes GM Don Maloney.
Regier spent 17 years as Buffalo's general manager, the longest tenure in the franchise's 44-year history. He helped lead the Sabres to the 1999 Stanley Cup final and the Eastern Conference final four times.
The 58-year-old oversaw all aspects of Buffalo's hockey operations and for the franchise's AHL affiliate, the Rochester Americans.
I kept refreshing the page on the NHL website after the second round and I was shocked he lasted that long. I'm sure the Coyotes were pretty happy to get him. He's such a good player and he plays big in big games.
— Arizona Coyotes forward Henrik Samuelsson on prospect Edgars Kulda being draftedd