Rugged forward Derek Dorsett, who took a boarding penalty that led to a goal in the third period of the Rangers' 3-0 loss Sunday, sat out Monday for the first time in these playoffs, along with forward Daniel Carcillo and defenceman John Moore.
Forwards Jesper Fast and J.T. Miller, and defenceman Raphael Diaz joined the lineup. Fast and Miller both played in two games of New York's first-round victory over Philadelphia. Diaz is making his post-season debut.
Vigneault made changes after each loss of the first round, with Carcillo going in or coming out each time. The Rangers won all three games after each loss to Philadelphia.
The Penguins made no changes after tying the series 1-1 Sunday.