Bishop dove to make a glove save and hit the ice hard, landing awkwardly on his left wrist. He was helped off the ice and appeared to be in discomfort. Bishop made three saves before he was replaced by Anders Lindback, who stopped all 25 shots he faced in a 3-0 victory.
Lightning coach Jon Cooper said Bishop will not play Thursday night against the Philadelphia Flyers, a game he was now slated to start.
"Let's just wait and see what happens here," Cooper said. "No sense in speculating. He's either going to be ready to go or he's not. I'm really confident in what we have, especially after watching the performance tonight."
Cooper wasn't sure about the severity of Bishop's injury, but he expressed confidence in Lindback's ability to carry the team.
"When Bishop went down, nobody flinched," Cooper said. "Actually, I think we got up a little bit on the bench. There was no panic by our guys. They know how hard Lindback has worked. It's his turn."
Bishop, who was appearing in his 63rd game this season, has a 37-14-7 record in 62 games, with a 2.23 goals-against average and a save percentage of .924. However, he has lost three of his past four decisions.
Bishop was placed on injured reserve on Jan. 6, one day after spraining his right wrist in the first period of the Lightning's game against the Edmonton Oilers. He returned on Jan. 14, allowing one goal in a 2-1 victory against the New York Rangers.