Bernier was making his fifth straight start since returning from a lower body injury that kept him out of five games.
The injury means Reimer will be counted on to keep the Leafs' slim playoff chances alive. Toronto trails Columbus by one point for the final playoff spot in the Eastern Conference, but the Blue Jackets have played two fewer games.
The Leafs are expected to recall Drew MacIntyre from the AHL's Toronto Marlies to fill the second goaltender spot on the bench.
Well, for me this one's concerning, the way we performed. Because three games in, playing a desperate team on the road, I was expecting something else than this. Right now, I'm just disappointed. The other games, I thought we did some things that you can build off your game. There wasn't a lot accomplished in tonight's game.
— Blue Jackets coach Todd Richards after a 4-2 loss to the Sabres on Monday dropped Columbus to 0-3-0
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