Prout may fill in for Fedor Tyutin, who missed Thursday's practice with an undisclosed illness.
The 23-year-old Prout has two assists, 31 penalty minutes and 41 blocked shots in 25 games with Columbus this season. He had a goal and six assists with 27 penalty minutes and a plus-15 rating in 28 games with the Blue Jackets last season.
Columbus' seventh pick, 154th overall, in the 2010 NHL draft, the 6-foot-3, 222-pound Prout has one goal and eight assists in 58 career NHL games.
I don't know the room very well yet. I don't know how we're going to react in certain situations. We've had a couple of minor tests throughout the [preseason] ... We'll get to know each other as the year goes on. We'll figure it out.
— Oilers coach Todd McLellan on starting the 2015-16 season without a captain
TONIGHT ON NHL NETWORK
5:00 ET: NHL Live Powered by Constellation 7:00 ET: NHL Tonight