The 36-year-old Handzus was sidelined by an upper-body injury earlier in the season. He has one goal and three assists in 13 games.
While Handzus is ready to return, forwards Andrew Shaw and Bryan Bickell have been ruled out for Friday night's game. Shaw (upper body) could return as soon as Sunday against Florida, while Bickell (lower body) is expected to begin skating again in the next week.
Rookie goaltender Antti Raanta got his third career start for Chicago and his first at home.
It's such a privilege to be one of these 80 great players to do this milestone, and it doesn't get better than this doing it where I started. It means a lot to me. A big thanks goes to all the players tonight who helped me to achieve that and also all the players through my career.
— Chicago Blackhawks forward Marian Hossa after scoring his 1,000th career point on Thursday night in Ottawa