Semin was injured Saturday during the Hurricanes' 4-2 loss to the St. Louis Blues on a hit by Blues defenseman Alex Pietrangelo. Semin returned to the ice briefly after the hit, but left the game for good in the second period.
The 29-year-old was out of the lineup Monday against the Boston Bruins.
Semin, who was second on the Hurricanes with 44 points last season, has three goals and six assists in 20 games this season.
I remember the first time at Wrigley Field all of us had the long johns, the turtlenecks and the extra equipment because we were afraid of being cold. Halfway through the first period everybody's ripping everything off and we just ended up wearing what we would normally wear for a game at the United Center.
— Chicago Blackhawks forward Patrick Sharp on the 2009 Bridgestone NHL Winter Classic