Semin was injured Saturday during the Hurricanes' 4-2 loss to the St. Louis Blues on a hit by Blues defenseman Alex Pietrangelo. Semin returned to the ice briefly after the hit, but left the game for good in the second period.
The 29-year-old was out of the lineup Monday against the Boston Bruins.
Semin, who was second on the Hurricanes with 44 points last season, has three goals and six assists in 20 games this season.
There's not much to say. We played like [garbage]. I think every guy in the room should be completely embarrassed about how they played tonight. Every single person. To start a road trip, one of the biggest road trips and have a division rival chasing you down and have a ton on the line, it's ridiculous how we played tonight.
— Anaheim forward Andrew Cogliano after the Ducks' 7-2 loss to the Flames on Wednesday