Semin was injured Saturday during the Hurricanes' 4-2 loss to the St. Louis Blues on a hit by Blues defenseman Alex Pietrangelo. Semin returned to the ice briefly after the hit, but left the game for good in the second period.
The 29-year-old was out of the lineup Monday against the Boston Bruins.
Semin, who was second on the Hurricanes with 44 points last season, has three goals and six assists in 20 games this season.
I downplayed the first one because I thought it's just a hockey game. We just want to win the game; it's against our rival and we want the two points. I downplayed it, but now having gone through the first one I look back and say, 'Geez, that was really cool.' I think as I've grown a bit older I've got a lot more appreciation for what we're allowed to do every day.
— Capitals forward Brooks Laich on the 2015 Bridgestone NHL Winter Classic, the second one of his career after 2011 in Pittsburgh