Brad Richardson, Mike Santorelli and Zack Kassian also scored for the Canucks, who had lost all five regular season meetings between the teams the past two seasons and were swept by San Jose in the first round of the playoffs last spring.
Joe Thornton and Mike Brown scored for the Sharks, who lost their fourth straight game, but just the second in regulation all season.
Antti Niemi allowed four goals on 12 shots before being replaced early in the second period as the Canucks controlled the play for much of the first 40 minutes and weathered a strong push from San Jose in the third.
This team has been a real treat to say you've been the head coach of them. I'm extremely proud of this group ... after the disappointment of (the Game 6 loss) is digested, it's always a lot easier as a coach when your team has emptied its tank, and that team emptied its tank for me for three months.
— Senators coach Dave Cameron after getting eliminated in the first round by the Canadiens