It was a rough night all around for the Senators as the other half of the team was beat 5-2 by the Islanders in Barrie, Ont.
The Senators seemed to struggle right from the start.
Wetmore opened the scoring 16:48 into the first period. Anderson made the stop on Kirill Kabanov's wraparound, but Wetmore buried the rebound. Less than a minute later Strome put the Isles ahead 2-0.
The Islanders made it 3-0 in the second on Pulock's power-play goal as he beat a screened Anderson. Nelson's goal just over three minutes later left Senators coach Paul MacLean fuming as he lit into his team during a commercial break.
Shortly after the Senators showed some life as Pageau took a great pass from Cody Ceci to get on the board.
The Senators finally managed to create some chances in the third, but Reiter was solid in relief of Nabokov.