Brenden Morrow added his first playoff goal in more than five years, Tomas Vokoun made 19 saves and the Penguins rode their superstar captain to their fourth straight victory.
Crosby beat Craig Anderson three times in the game's first 22 minutes, sending the goalie to the bench after stopping 18 of 21 shots.
Kyle Turris, Colin Greening and Jean-Gabriel Pageau scored for the Senators, but couldn't stop Ottawa from falling into a deep hole against the Eastern Conference's top seed. The Senators have never won a playoff series after dropping the first two games.
That's a really tough thing to play through; when you finally are thrown out there, the game is fast, intense, every single play matters, you've got to find a way to play through that and make smart plays. So it's a huge testament to [Vermette] and some other individuals in our locker room that are putting their own ego, their own wants and needs aside, and are ready for those opportunities when they do come.
— Blackhawks captain Jonathan Toews on teammate Antoine Vermette, who returned from being a healthy scratch in Game 3 to score the double-overtime winner in Game 4