Joe Vitale added his first goal in more than a year for the Penguins, who have beaten the Bruins five consecutive times.
Tyler Seguin scored his 10th goal for Boston, and Tuukka Rask made 16 saves but couldn't stop the Bruins from losing to Pittsburgh for the second time in less than a week.
The Penguins scored three times in the final 7 minutes Tuesday to steal a 3-2 victory. There were no dramatics necessary this time, as hockey's hottest team never trailed to remain unbeaten in March.
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