Fedotenko injured his hand less than two minutes into Tuesday night's game against the Atlanta Thrashers in a one-punch fight against former Penguin Colby Armstrong.
Fedotenko decked Armstrong with the punch, although Fedotenko rarely fights.
The Penguins say Fedotenko has been placed on injured reserve.
Forward Pascal Dupuis sustained an unspecified injury in the same game, but coach Michel Therrien has said he could return to the lineup in the next few days.
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