DeKeyser broke his right thumb in the third period of Detroit's 5-4 overtime win over the Ducks on Thursday night that evened the series at 1-1.
Babcock has said the Red Wings wouldn't have rallied for a spot in a 22nd straight post-season without DeKeyser. Now, they have to try to advance without him on the blue line.
The Red Wings hope home ice is an advantage that helps them take a 2-1 lead in the first-round series Saturday night in Game 3.
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