|On Jan. 16, 2011, Ruff became the 16th coach in NHL history to win 500 games. Two days later, Ruff became the winningest one-team coach in NHL history when his 501st victory eclipsed Toe Blake's 500 in Montreal.
The 2009-10 season had added meaning for Ruff as he served on the Team Canada coaching staff at the Vancouver Winter Olympics. Ruff capped off the 2008-09 season by guiding Team Canada to a silver medal at the IIHF World Hockey Championships in Switzerland. In Ruff's first international coaching experience, he led Canada to a 7-1-1 record in the 17-day tournament. The Canadian side suffered their only regulation loss to the Russians by a score of 2-1 in the Gold medal game. Ruff has compiled a career record of 438-352-112, with his 438 wins tops among all NHL coaches with their current team. Ruff is 19th all-time in NHL career wins, and sixth overall among active coaches in wins. On October 15, 2008, Ruff became the 23rd coach in NHL history to win 400 games, and just the 7th to win 400 games for one team. Ruff, the all-time winningest coach in Sabres' history, has a .591 playoff winning percentage and is the Sabres' all-time leader in playoff games coached (88), and wins (52), surpassing Scotty Bowman's mark of 18 wins (set over five seasons). His 52 career playoff wins are tied for 14th place on the all-time list. Among coaches with 40 or more playoff wins, Ruff is in the top 5 in terms of career winning percentage. In only his second season as head coach, Ruff led the 1998-99 Sabres to their first Stanley Cup Finals appearance in 24 years and established himself as one of the league's top coaches. He also achieved a club record that season for the most wins (14) in one playoff year. In the process, Ruff became only the third head coach under the present Stanley Cup Playoff format to lead his team to the Conference Finals in each of his first two seasons. During the 2006-07, the Sabres' had their finest year under Ruff statistically when the team won a franchise-record 53 games and captured the first Presidents' Trophy in club history, while leading both the Northeast Division and Eastern Conference from wire-to-wire. This was also the first time in franchise history they've posted back-to-back 50-win seasons. Buffalo returned to the Eastern Conference Finals for the second consecutive season, and the fourth time under Ruff's guidance. On April 5, 2007, a 5-4 Buffalo victory over Ottawa made him the 31st coach in NHL history to record 300 career wins, and the 16th in NHL history to reach the milestone with the same team.