The Devils forced Panthers coach Kevin Dineen to pull starter Jose Theodore just 6:16 into the first after the veteran netminder allowed three goals on six shots.
The Panthers, who rallied from a 3-0 deficit to open a 4-3 lead through two periods, chased New Jersey starter Martin Brodeur in favor of Johan Hedberg 2:18 into the second after the future Hall of Fame goalie yielded three goals on 12 shots.
The last time Brodeur was pulled from playoff game was in a 6-0 loss to the Carolina Hurricanes in Game 1 of the 2006 conference semifinal round.
I think everyone left it out there. Every game this season, regular season and playoffs, we played as hard as we could. We're not out of the playoffs right now because of lack of effort, and that's all that we can ask of each other.
— Predators defenseman Seth Jones after Nashville was eliminated by Chicago in Game 6 on Saturday