The Blues, coming off a 3-2 overtime defeat against the Ottawa Senators on Monday, arrived in St. Louis in the early hours of Tuesday morning and did so without three top forwards at their disposal.
Second-line forwards Vladimir Sobotka and Jaden Schwartz did not play Monday because of upper-body injuries, and the Blues (22-6-4) lost captain David Backes in the third period with an upper-body injury after a head-on-head collision with the Senators' Colin Greening.
The Sharks (20-7-6) are in the middle of one of their toughest stretches of the season at 1-4-1, but they have given the Blues two of their six regulation losses, outscoring St. Louis 12-5.
"The starts have been important both nights," said Sharks coach Todd McLellan, referring to their 2-0 first-period lead at Scottrade Center Oct. 15 and 4-0 first-period lead Nov. 29 in San Jose. "The power play and penalty kill have been good both nights. Goaltending's been very good and we've played a competitive game. Without that, you really limit your opportunity to win. That type of formula doesn't guarantee you success, but it gives you a better chance."
San Jose, which has been outscored 19-12 in the past six games, is simply looking to get back to the way it was playing when it was 19-3-5 and holding the best record in the League.
"Our relentless kind of effort and energy that we had at the beginning of the year is missing a little bit," said Sharks defenseman Dan Boyle, who returns to the scene of where he was the recipient of a check from behind by the Blues' Maxim Lapierre that forced him to miss seven games.
"... Some of that is just the grind of the season and every team goes through it. You've just got to find a way to get that back."
Backes will not play, and Sobotka and Schwartz remain questionable.
The projected lineups for the Sharks and Blues:
Injured: Scott Hannan (upper body)