Winchester missed the past four games because of a lower-body injury sustained in a 4-1 loss against the Edmonton Oilers on Nov. 21. Winchester, signed as a free agent this summer after he spent all of 2012-13 playing in Europe, was one of Florida's most productive forwards earlier this season.
"He works hard in all three areas of the rink," Panthers interim coach Peter Horachek said after the morning skate Saturday. "He's not afraid to go into the hard areas. He's pretty good on the walls. That's one of the areas before I got here that he was one of the players who were doing what they needed to do and living up to their responsibilities. He's a good kid, he works hard, and he's kind of a workhorse that people can follow and use as an example."
The Panthers will again be without Tomas Kopecky. The veteran forward also was injured in the loss at Edmonton.
Veteran Tim Thomas is expected to make his 11th consecutive start in net for the Panthers, who beat Pittsburgh 6-3 in their home opener on Oct. 11.
Pittsburgh goalie Jeff Zatkoff had a less-than-memorable NHL debut when he allowed six goals on 30 shots.
There's a possibility Zatkoff could get another shot at the Panthers on Saturday given the Penguins played Friday at the Tampa Bay Lightning. Coach Dan Bylsma also might elect to go again with Marc-André Fleury who made 21 saves in a 3-0 shutout victory.
It was a solid bounce-back effort for Fleury, who was pulled after giving up three goals on 11 shots in the first period of a 6-5 shootout victory against the Toronto Maple Leafs on Wednesday.
Zatkoff's most recent start came Nov. 22 when he allowed three goals on 35 shots in a 4-3 victory against the New York Islanders.
This is the sixth back-to-back set for the Penguins so far this season, and Fleury and Zatkoff have split starts five times.
The Penguins, who wrap up their three-game road trip Tuesday against the New York Islanders, did not hold a morning skate Saturday.
Here are the projected lineups for the Penguins and Panthers at BB&T Center: