The Avalanche have a 14-4-0 record but have lost two in a row for the first time this season and are coming off a 7-3 loss Thursday to the St. Louis Blues.
"There's no reason for us not to be confident," Roy said. "We have 28 points and if you look at the segment of 20 games, you do that four times it's 112 points without winning the next two [games]. It's not only going to help you make the playoffs, you're going to be pretty close to be first overall.
"We're going to go through games like this in a season. The good thing is we talked about it. There's an area in our game that needs to improve, and that's our game management. We can't take penalties in the offensive zone. We need to be smarter. There's a few plays defensively where we were not as sharp.
"We should be very happy with our start, but we cannot be satisfied. It's a big difference. When you're not satisfied it means you're aware there are things to improve in our game. The good thing is we're aware of those things."
Defenseman Matt Hunwick will replace Andre Benoit, who sustained a wrist injury against the Blues. Hunwick has yet to play a game for the Avalanche this season. He played in five games for the Lake Erie Monsters in the American Hockey League and had two assists.
The Panthers will be playing the second game of a five-game road trip after losing 3-2 to the Minnesota Wild on Friday. They've gone 1-1-1 in the second game when playing back-to-back and have lost three of four games since Peter Horachek replaced Kevin Dineen as coach Nov. 8.
Here are the projected lineups for the Panthers and Avalanche:
NOTES: Avalanche coach Patrick Roy said Saturday that right wing Alex Tanguay, who hurt his knee Nov. 2 against the Montreal Canadiens, will be sidelined indefinitely. "It's hard to pinpoint when he's going to come back," Roy said.