The Blue Jackets will face off against the Edmonton Oilers on Thursday at Rexall Place.
Wisniewski has missed the past 14 games while recovering from a broken foot sustained Feb. 24 at United Center against the Chicago Blackhawks.
Wisniewski has three goals and nine points in 15 games this season. The 6-foot, 208-pound defender led the Blue Jackets with three power play goals and ranked fifth on the club in points at the time of his injury.
Dubinsky is dealing with a lower-body injury that has sidelined him the past three games. The 26-year-old forward has one goal, nine points and 38 hits in 19 games with Columbus this season. He also missed 11 games between Feb. 18 and March 10 with a knee injury.