TSN's James Duthie reported that Sharp has a separated shoulder, posting on his official Twitter account that Sharp has "a fairly severe AC joint shoulder separation."
In 24 games this season, Sharp has five goals and 18 points.
The Blackhawks meet the Avalanche again Friday at Pepsi Center (9 p.m. ET, NHLN-US), trying to extend their point streak to 25 games to start this season, and 31 stretching to the end of the 2011-12 regular season.
It's an incredible feeling just to see it go in and see the Joe go pretty crazy. Ever since the introduction there, I was kind of feeling the nerves, and to put that one home, I started to feel comfortable and I thought my play started to pick up.
— Nineteen-year-old Red Wings forward Dylan Larkin after scoring a goal in his NHL debut
TONIGHT ON NHL NETWORK
6:30 ET: Hockey Central Saturday: Hockey Tonight 7:00 ET: NHL Hockey: MTL @ BOS (Live Game) 10:00 ET: NHL Tonight