The Blue Jackets are fourth in the Metropolitan Division with 10 points, eight behind the first-place Penguins. Columbus will have a chance to cut into that lead during the home-and-home set.
Forward Brandon Dubinsky said the Blue Jackets will need to come out strong Friday to set themselves up for the rematch Saturday in Columbus.
"You have to make it a hard game," Dubinsky said. "You have to come out, be ready to compete right from the get-go. We know these guys come hard at home. They play with speed. They generate a lot of speed through the neutral zone and they got some top-end guys.
"We have to find a way to stay disciplined, stay out of the box and be ready to play a physical and hard game."