Boston is coming off a dismal performance in Thursday's 6-0 loss to Toronto. The Bruins allowed three power-play goals, one in each period, to slip to 0-2-1 in their last three at home.
"I thought we had probably three or four players going that had sufficient energy to be effective," Bruins coach Mike Sullivan said. "We tried to throw some different line combinations to spark the team, but once again, I think it boiled down to our special teams.
"They win and lose games for you and tonight, they lost it for us."
The Bruins are second to last in the league in penalty killing at 76.5 percent. Only Edmonton had a worse mark entering Friday's games.
"We're not going to make any excuses," said Boston center Joe Thornton. "That was a big game for us and to come out like that is not a good sign. But we've got to keep our heads up. We've got Philly on Saturday and obviously Ottawa after that. We've got big games coming up and we've got to be ready."
Bruins goaltender Felix Potvin is 1-4-2 in his last seven starts, and Boston is just 1-3-1-1 in its last six games overall.
"We had a pretty good stretch at home before the last three games and we have to get it back," Potvin said.
Philadelphia should give the Bruins' struggling penalty-killing unit plenty of trouble. The Flyers top the league on the man advantage, scoring at 26.3 percent clip.
Philadelphia capitalized on one of two power-play opportunities in its 3-2 victory over the Phoenix Coyotes on Friday. The win extended the Flyers' season-opening home unbeaten streak to 13 (11-0-2).
"This was a good win for us where everyone contributed," said Philadelphia coach Ken Hitchcock. "We used all four lines tonight pretty much until the last four or five minutes, which worked well."
The Flyers have just one loss in their last 14 games overall, going 11-1-2-0.