John Tavares scored twice in the first period and Travis Hamonic and Matt Moulson each assisted on three goals as the Islanders built up a five-goal lead and held off the Predators in their lone preseason game at Nassau Coliseum.
Tavares, wearing the "C" at the Coliseum for the first time, scored 1:25 into the game and fired home a rebound at 13:38 to put the Islanders ahead to stay. Lubomir Visnovsky, Colin McDonald and Josh Bailey also scored for the Islanders, who conclude their preseason on the road against the Ottawa Senators on Sunday.
The Islanders had been shut out in back-to-back games before scoring six times on Friday.
"I don't think we thought about it too much," Tavares said. "We had a good week of practice. Physically the guys were recharged and excited to get out there tonight, to play at home. We did some good things, but we can still be a lot better."
Craig Smith scored twice for the Predators, who trailed 6-1 before beating Evgeni Nabokov (23 saves) in the final 8 1/2 minutes. Nashville, which didn't arrive on Long Island until a couple of hours before game time due to a flight delay, opens its season on the road against the St. Louis Blues on Thursday.